Publications

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SF Chan, BP Hejblum, A Chakrabortty, T Cai (2019). Semi-Supervised Estimation of Covariance with Application to Phenome-wide Association Studies with Electronic Medical Records Data. Stat Methods Med Res, in press.

S Ajana, A Niyazi, L Bretillon, BP Hejblum, H Jacqmin-Gadda, C Delcourt (2019). Benefits of dimension reduction in penalized regression methods for high dimensional grouped data: a case study in low sample size. Bioinformatics, btz135, in press.

DY Low*, S Lefèvre‐Arbogast*, R González‐Domínguez, M Urpi‐Sarda, P Micheau, M Petera, D Centeno, S Durand, E Pujos‐Guillot, A Korosi, PJ Lucassen, L Aigner, C Proust‐Lima, BP Hejblum, C Helmer, C Andres‐Lacueva, S Thuret, C Samieri*, C Manach* (2019). Diet‐Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort. Mol. Nutr. Food Res., 63(18):1900177.

BP Hejblum, C Alkhassim, R Gottardo, F Caron, R Thiébaut (2019). Sequential Dirichlet process mixture of skew t-distributions for model-based clustering of flow cytometry data. Ann. Appl. Stat., 13(1):638-660.

Preprint PDF R package Article

R Thiébaut, BP Hejblum, H Hocini, H Bonnabau, J Skinner, M Montes, C Lacabaratz, L Richert, K Palucka, J Banchereau, Y Levy (2019). Gene expression signatures associated with immune and virological responses to therapeutic vaccination with Dendritic Cells in HIV-infected individuals. Front. Immunol., 10:874, 2019.

BP Hejblum, GM Weber, KP Liao, NP Palmer, S Churchill, NA Shadick, P Szolovits, SM Murphy, IS Kohane, T Cai (2019). Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Sci. Data, 6:180298.

PDF R package Article

D Commenges, C Alkhassim, R Gottardo, BP Hejblum, R Thiébaut (2018). cytometree: a binary tree algorithm for automatic gating in cytometry analysis. Cytom. A, 93(11):1132-1140.

Preprint Article R package

BP Hejblum, J Cui, LJ Lahey, A Cagan, JA Sparks, J Sokolove, T Cai, KP Liao (2018). Association between anti-citrullinated fibrinogen antibodies and coronary artery disease in rheumatoid arthritis. Arthritis Care Res, 70(7):1113-1117.

JA Sinnott, F Cai, S Yu, BP Hejblum, C Huong, IS Kohane, KP Liao (2018). PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies. JAMIA, 25(10):1359-1365.

S Lefèvre-Arbogast, D Gaudout, J Bensalem, L Letenneur, JF Dartigues, BP Hejblum, C Féart, C Delcourt, C Samieri (2018). Pattern of polyphenol intake and the long-term risk of dementia in older persons. Neurology, 90(22):e1979-e1988.

M Neykov, BP Hejblum, JA Sinnott (2018). Kernel Machine Score Test for Pathway Analysis in the Presence of Semi-Competing Risks. Stat Methods in Med Res, 27(4):1099-1114.

Article R package

KP Liao*, JA Sparks*, BP Hejblum, IH Kuo, J Cui, LJ Lahey, A Cagan, VS Gainer, W Liu, TT Cai, J Sokolove, T Cai (2017). Phenome-wide association study of autoantibodies to citrullinated and non-citrullinated epitopes in rheumatoid arthritis. Arthritis & Rheumatology, 69(4):742-749.

D Agniel, BP Hejblum (2017). Variance component score test for time-course gene set analysis of longitudinal RNA-seq data. Biostatistics, 18(4):589–604.

Preprint PDF Article R package

A Rechtien, L Richert, H Lorenzo, G Martrus, BP Hejblum, C Dahlke, R Kasonta, M Zinser, H Stubbe, U Matschl, A Lohse, V Krähling, M Eickmann, S Becker, VEBCON Consortium, R Thiébaut, M Altfeld, M Addo (2017). Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV. Cell Reports, 20(9):2251-2261.

B Liquet, P Lafaye de Micheaux, BP Hejblum, R Thiébaut (2016). Group and Sparse Group Partial Least Square Approaches Applied in Genomics Context. Bioinformatics, 32(1):35-42.

PDF Article R package

BP Hejblum, J Skinner, R Thiébaut (2015). Time-Course Gene Set Analysis for Longitudinal Gene Expression Data. PLoS Comput Biol, 11(6):e1004310.

PDF Code Article R package

R Thiébaut, B Hejblum, L Richert (2014). The analysis of 'Big Data' in clinical research. Rev Epidemiol Sante Publique, 62(1):1-4.

D Furman*, BP Hejblum*, N Simon, V Jojic, CL Dekker, R Thiébaut, RJ Tibshirani, MM Davis (2014). A systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination. Proc Natl Acad Sci USA, 111(2):869-874.

D Commenges, BP Hejblum (2013). Evidence synthesis through a degradation model applied to myocardial infarction. LiDA, 19(1):1-18.